Dab tsi yog qhov txawv ntawm tawv gelatin capsules thiab HPMC capsules?

Hard gelatin capsules thiab hydroxypropyl methylcellulose (HPMC) capsules yog ob qho tib si feem ntau siv los ua cov ntaub ntawv siv rau encapsulating kws tshuaj, tshuaj noj, thiab lwm yam tshuaj.Thaum lawv ua haujlwm zoo ib yam, muaj ntau qhov sib txawv ntawm ob hom tshuaj ntsiav:

1. Kev sib xyaw:
   • Hard Gelatin Capsules: Hard gelatin capsules yog tsim los ntawm gelatin, ib qho protein tau los ntawm cov tsiaj txhu, feem ntau bovine lossis porcine collagen.
   • HPMC Capsules: HPMC capsules yog tsim los ntawm hydroxypropyl methylcellulose, semisynthetic polymer muab tau los ntawm cellulose, ib txwm tshwm sim polymer pom nyob rau hauv cov nroj tsuag cell phab ntsa.
2. Qhov chaw:
   • Hard Gelatin Capsules: Gelatin capsules yog muab los ntawm cov tsiaj txhu, ua rau lawv tsis haum rau cov neeg tsis noj nqaij thiab cov tib neeg uas muaj kev txwv kev noj zaub mov muaj feem xyuam rau cov khoom tsiaj.
   • HPMC Capsules: HPMC capsules yog tsim los ntawm cov khoom siv cog, ua rau lawv tsim nyog rau cov neeg tsis noj nqaij thiab cov tib neeg uas zam cov khoom los ntawm cov tsiaj.
3. Kev ruaj ntseg:
   • Hard Gelatin Capsules: Gelatin capsules tej zaum yuav raug cuam tshuam los ntawm kev sib txuas, brittleness, thiab deformation nyob rau hauv tej yam kev mob ib puag ncig, xws li high humidity los yog kub hloov.
   • HPMC Capsules: HPMC capsules muaj kev ruaj ntseg zoo dua hauv ntau qhov chaw ib puag ncig thiab tsis tshua muaj kev sib txuas, brittleness, thiab deformation piv rau gelatin capsules.
4. Moisture Resistance:
   • Hard Gelatin Capsules: Gelatin capsules yog hygroscopic thiab tuaj yeem nqus dej noo, uas tuaj yeem cuam tshuam rau kev ruaj ntseg ntawm cov dej noo-rhiab formulations thiab cov khoom xyaw.
   • HPMC Capsules: HPMC capsules muab cov dej noo zoo dua piv rau gelatin capsules, ua rau lawv tsim nyog rau cov qauv uas xav tau kev tiv thaiv kev ya raws.
5. Kev tsim khoom:
   • Hard Gelatin Capsules: Gelatin capsules feem ntau yog tsim los ntawm cov txheej txheem molding, qhov twg gelatin tov yog coated rau tus pin pwm, qhuav, thiab ces stripped tawm los ua lub capsule halves.
   • HPMC Capsules: HPMC capsules yog tsim los siv cov txheej txheem thermoforming los yog extrusion, qhov twg HPMC hmoov yog tov nrog dej thiab lwm yam additives, tsim rau hauv ib tug gel, molded rau hauv capsule shells, thiab ces qhuav.
6. Regulatory Considerations:
   • Hard Gelatin Capsules: Gelatin capsules yuav xav tau kev tswj xyuas tshwj xeeb, tshwj xeeb tshaj yog muaj feem xyuam nrog cov khoom siv thiab qhov zoo ntawm cov gelatin siv.
   • HPMC Capsules: HPMC capsules feem ntau suav hais tias yog ib qho kev xaiv zoo tshaj plaws hauv kev tswj hwm cov ntsiab lus uas cov neeg tsis noj nqaij lossis cov nroj tsuag xav tau los yog xav tau.

Zuag qhia tag nrho, thaum ob qho tib si tawv gelatin capsules thiab HPMC capsules ua cov ntaub ntawv siv tau zoo rau cov tshuaj encapsulating thiab lwm yam tshuaj, lawv txawv nyob rau hauv muaj pes tsawg leeg, qhov chaw, stability, noo noo tsis kam, txheej txheem tsim, thiab kev tswj xyuas.Qhov kev xaiv ntawm ob hom tshuaj ntsiav yog nyob ntawm cov yam ntxwv xws li kev nyiam noj zaub mov, kev tsim qauv, ib puag ncig, thiab kev saib xyuas kev tswj hwm.