Hydroxypropylmethylcellulose (HPMC) yog ib qho kev hloov kho hluavtaws ntawm cellulose, ib qho polymer ntuj pom nyob rau hauv cov phab ntsa ntawm cov nroj tsuag.Thaum HPMC nws tus kheej tsis nruj me ntsis biopolymer vim nws yog chemically synthesized, nws yog feem ntau suav hais tias yog ib tug semi- Synthetic los yog hloov biopolymers.
A. Taw qhia rau hydroxypropyl methylcellulose:
Hydroxypropyl methylcellulose (HPMC):
Hydroxypropylmethylcellulose (HPMC) yog ib qho derivative ntawm cellulose, linear polymer tsim los ntawm cov piam thaj units.Cellulose yog lub ntsiab structural tivthaiv ntawm cov nroj tsuag cell phab ntsa.HPMC yog tsim los ntawm kev hloov kho cellulose los ntawm kev ntxiv hydroxypropyl thiab methyl pawg.
B. Qauv thiab kev ua haujlwm:
1.Chemical qauv:
Cov qauv tshuaj ntawm HPMC muaj cov cellulose caj qaum cov kabmob uas muaj hydroxypropyl thiab methyl pawg.Degree ntawm kev hloov pauv (DS) yog hais txog qhov nruab nrab ntawm cov hydroxypropyl thiab methyl pawg hauv ib chav tsev piam thaj hauv cov saw cellulose.Qhov kev hloov pauv no hloov pauv lub cev thiab tshuaj lom neeg ntawm cellulose, ua rau muaj ntau yam ntawm HPMC qib nrog sib txawv viscosities, solubility thiab gel zog.
2. Lub cev muaj zog:
Solubility: HPMC yaj hauv dej thiab tsim cov kev daws teeb meem, ua rau nws muaj txiaj ntsig zoo hauv ntau yam kev siv xws li tshuaj, khoom noj, thiab kev tsim kho.
Viscosity: Lub viscosity ntawm HPMC cov tshuaj tuaj yeem tswj tau los ntawm kev kho cov qib kev hloov pauv thiab qhov hnyav molecular ntawm cov polymer.Cov cuab yeej no tseem ceeb heev rau kev siv xws li cov tshuaj formulations thiab cov ntaub ntawv tsim kho.
3. Muaj nuj nqi:
Cov Thickeners: HPMC feem ntau yog siv los ua cov thickener hauv cov khoom noj, tshuaj, thiab cov khoom tu tus kheej.
Film Forming: Nws tuaj yeem tsim cov yeeb yaj kiab thiab tuaj yeem siv rau txheej tshuaj ntsiav tshuaj thiab tshuaj ntsiav, nrog rau kev tsim cov yeeb yaj kiab rau ntau yam kev siv.
Kev tuav dej: HPMC paub txog nws cov khoom tuav dej, pab txhim kho kev ua haujlwm thiab dej ntawm cov khoom siv hauv tsev xws li cov khoom siv cement.
C. Kev siv HPMC:
1. Tshuaj:
Tablet Txheej: HPMC yog siv los tsim cov ntsiav tshuaj txheej los tswj cov tshuaj tso tawm thiab txhim kho kev ruaj ntseg.
Kev xa tshuaj ntawm qhov ncauj: Cov biocompatibility thiab tswj kev tso tawm ntawm HPMC ua rau nws tsim nyog rau kev xa tshuaj hauv qhov ncauj.
2. Kev tsim kho kev lag luam:
Cov khoom siv khib nyiab thiab cement: HPMC yog siv rau hauv cov khoom siv los txhim kho cov dej tuav, ua haujlwm tau zoo thiab adhesion.
3. Khoom noj khoom haus kev lag luam:
Thickeners thiab Stabilizers: HPMC yog siv los ua cov thickener thiab stabilizer hauv cov khoom noj los txhim kho kev ntxhib los mos thiab ruaj khov.
4. Cov khoom siv tu tus kheej:
Cosmetic Formulation: HPMC tau muab tso rau hauv cov tshuaj pleev ib ce rau nws cov yeeb yaj kiab tsim thiab thickening.
5. Xim thiab Txheej:
Waterborne coatings: Hauv kev lag luam coatings, HPMC yog siv nyob rau hauv waterborne formulations los txhim kho rheology thiab tiv thaiv pigment settling.
6. Kev xav txog ib puag ncig:
Thaum HPMC nws tus kheej tsis yog ib qho biodegradable polymer tag nrho, nws cov keeb kwm cellulosic ua rau nws tus phooj ywg ib puag ncig piv rau cov khoom siv hluavtaws tag nrho.HPMC tuaj yeem biodegrade nyob rau hauv tej yam kev mob, thiab nws siv nyob rau hauv sustainable thiab biodegradable formulations yog ib cheeb tsam ntawm kev tshawb fawb tsis tu ncua.
Hydroxypropylmethylcellulose (HPMC) yog ib qho khoom siv hluav taws xob semi-synthetic polymer muab los ntawm cellulose.Nws cov khoom tshwj xeeb ua rau nws muaj txiaj ntsig hauv ntau yam kev lag luam xws li tshuaj, kev tsim kho, khoom noj khoom haus, kev saib xyuas tus kheej thiab xim.Txawm hais tias nws tsis yog daim ntawv ntshiab tshaj plaws ntawm biopolymer, nws cov keeb kwm ntawm cellulose thiab biodegradation muaj peev xwm yog nyob rau hauv txoj kab nrog kev xav tau ntau ntxiv rau cov ntaub ntawv ruaj khov hauv ntau daim ntawv thov.Kev tshawb fawb tsis tu ncua txuas ntxiv tshawb nrhiav txoj hauv kev los txhim kho ib puag ncig kev sib raug zoo ntawm HPMC thiab nthuav dav nws cov kev siv hauv kev tsim cov phooj ywg ib puag ncig.
Post lub sij hawm: Feb-07-2024