Txhawm rau kom sib piv CMC (carboxymethylcellulose) thiab HPMC (hydroxypropylmethylcellulose), peb yuav tsum nkag siab txog lawv cov khoom, kev siv, qhov zoo, qhov tsis zoo, thiab cov neeg siv tau. Ob leeg cellulose derivatives yog dav siv nyob rau hauv ntau yam lag luam, nrog rau cov kws, khoom noj khoom haus, tshuaj pleev ib ce thiab kev tsim kho. Txhua tus muaj cov khoom tshwj xeeb uas ua rau lawv haum rau ntau lub hom phiaj. Cia peb ua qhov sib piv qhov tob kom pom qhov twg yog qhov zoo dua hauv cov xwm txheej sib txawv.
1. Txhais thiab qauv:
CMC (carboxymethylcellulose): CMC yog cov dej-soluble cellulose derivative tsim los ntawm cov tshuaj tiv thaiv ntawm cellulose thiab chloroacetic acid. Nws muaj cov carboxymethyl pawg (-CH2-COOH) sib koom ua ke rau qee pawg hydroxyl ntawm glucopyranose monomers uas ua rau cov pob txha cellulose.
HPMC (hydroxypropyl methylcellulose): HPMC kuj yog cov dej-soluble cellulose derivative uas ua los ntawm kev kho cellulose nrog propylene oxide thiab methyl chloride. Nws muaj hydroxypropyl thiab methoxy pawg txuas nrog cellulose qaum.
2. Solubility:
CMC: Soluble hauv dej heev, tsim cov pob tshab, kua nplaum. Nws nthuav tawm tus cwj pwm pseudoplastic ntws, uas txhais tau hais tias nws cov viscosity txo qis hauv kev nyuaj siab shear.
HPMC: Tsis tas li soluble hauv dej, tsim cov kua nplaum me ntsis dua li CMC. Nws kuj pom tus cwj pwm pseudoplastic.
3.Rheological zog:
CMC: Qhia txog tus cwj pwm shear thinning, uas txhais tau hais tias nws cov viscosity txo nrog nce shear npaum li cas. Cov cuab yeej no ua rau nws tsim nyog rau cov ntawv thov uas yuav tsum tau ua kom tuab tab sis cov tshuaj yuav tsum tau ntws yooj yim hauv qab shear, xws li cov xim, cov tshuaj ntxuav tes thiab tshuaj.
HPMC: nthuav tawm tus cwj pwm zoo li rheological rau CMC, tab sis nws cov viscosity feem ntau yog siab dua ntawm qhov tsis tshua muaj siab. Nws muaj cov khoom ua yeeb yaj kiab zoo dua qub, ua rau nws tsim nyog rau kev siv xws li txheej txheej, nplaum thiab tswj-tso tshuaj formulations.
4. Kev ruaj ntseg:
CMC: Feem ntau ruaj khov nyob rau ntau yam ntawm pH thiab kub. Nws tuaj yeem zam cov theem nrab ntawm cov electrolytes.
HPMC: Ntau ruaj khov dua CMC nyob rau hauv acidic tej yam kev mob, tab sis tej zaum yuav undergo hydrolysis nyob rau hauv alkaline tej yam kev mob. Nws kuj yog ib qho rhiab rau divalent cations, uas tuaj yeem ua rau gelation lossis nag lossis daus.
5. Daim ntawv thov:
CMC: dav siv los ua thickener, stabilizer thiab dej-retaining agent nyob rau hauv cov khoom noj (xws li ice cream, sauce), tshuaj (xws li ntsiav tshuaj, ncua kev kawm ntawv) thiab tshuaj pleev ib ce (xws li qab zib, tshuaj pleev ib ce) industries.
HPMC: Feem ntau siv rau hauv cov khoom siv (piv txwv li, cement pobzeb adhesives, plaster, mortar), tshuaj (xws li, tshuaj-tso tawm ntsiav tshuaj, tshuaj kho qhov muag), thiab tshuaj pleev ib ce (piv txwv li, qhov muag tee, khoom tu tawv nqaij).
6. Toxicity thiab kev nyab xeeb:
CMC: Feem ntau lees paub tias muaj kev nyab xeeb (GRAS) los ntawm cov koom haum tswj hwm thaum siv nyob rau hauv cov kev txwv tshwj xeeb hauv cov ntawv thov zaub mov thiab tshuaj. Nws yog biodegradable thiab non-toxic.
HPMC: Kuj pom tias muaj kev nyab xeeb rau kev noj nyob rau hauv cov kev txwv pom zoo. Nws yog biocompatible thiab dav siv nyob rau hauv kev lag luam teb raws li kev tswj kev tso tawm tus neeg sawv cev thiab ntsiav tshuaj binder.
7. Nqi thiab Muaj:
CMC: Feem ntau yuav raug nqi ntau dua li HPMC. Nws tau yooj yim muaj los ntawm cov chaw muag khoom sib txawv thoob ntiaj teb.
HPMC: Tus nqi qis dua vim nws cov txheej txheem tsim khoom thiab qee zaum txwv cov khoom siv los ntawm qee tus neeg muag khoom.
8. Kev cuam tshuam ib puag ncig:
CMC: Biodegradable, muab los ntawm cov khoom siv txuas ntxiv dua tshiab (cellulose). Nws yog suav tias yog ib puag ncig tus phooj ywg.
HPMC: Tsis tas li biodegradable thiab muab tau los ntawm cellulose, yog li kuj zoo ib puag ncig.
Ob leeg CMC thiab HPMC muaj cov khoom tshwj xeeb uas ua rau lawv muaj txiaj ntsig ntxiv hauv ntau qhov kev lag luam. Qhov kev xaiv ntawm lawv nyob ntawm qhov kev thov tshwj xeeb xws li solubility, viscosity, stability thiab kev xav txog tus nqi. Feem ntau, CMC tej zaum yuav nyiam vim nws cov nqi qis dua, kev ruaj ntseg pH dav dua, thiab tsim nyog rau kev siv khoom noj thiab tshuaj pleev ib ce. HPMC, ntawm qhov tod tes, tej zaum yuav tau txais kev pom zoo rau nws cov viscosity siab dua, zoo dua cov yeeb yaj kiab tsim, thiab kev siv hauv cov tshuaj thiab cov khoom siv. Thaum kawg, kev xaiv yuav tsum yog raws li tag nrho cov kev xav ntawm cov yam ntxwv no thiab kev sib haum xeeb nrog kev siv.
Post lub sij hawm: Feb-21-2024