Hydroxypropyl Methylcellulose (HPMC) yog ntau yam polymer uas pom cov ntawv siv dav hauv ntau yam lag luam, suav nrog tshuaj, khoom noj, kev tsim kho, thiab tshuaj pleev ib ce.
1. Taw qhia rau HPMC:
Hydroxypropyl Methylcellulose (HPMC) yog semi-synthetic, inert, viscoelastic polymer muab tau los ntawm cellulose. Nws yog tsim los ntawm kev hloov kho tshuaj ntawm cellulose, uas koom nrog etherification ntawm alkali cellulose nrog propylene oxide thiab methyl chloride. Cov khoom uas tau tshwm sim yog xim dawb mus rau dawb, tsis muaj ntxhiab, thiab tsis qab ntsev hmoov uas yog soluble hauv dej tab sis insoluble hauv cov kuab tshuaj organic.
2. Cov qauv thiab cov khoom siv:
HPMC tus qauv muaj lub nraub qaum ntawm cellulose, ib qho khoom siv ntuj tsim los ntawm cov piam thaj txuas los ntawm β (1 → 4) glycosidic bonds. Hauv HPMC, qee pawg hydroxyl ntawm cov piam thaj tau hloov nrog 2-hydroxypropyl thiab methyl pawg. Qhov kev hloov pauv no hloov pauv cov khoom siv polymer piv rau cov cellulose ib txwm muaj, ua kom zoo dua solubility, viscosity, thiab muaj peev xwm tsim cov yeeb yaj kiab.
Cov khoom ntawm HPMC sib txawv nyob ntawm seb yam xws li qib kev hloov pauv (DS), qhov hnyav molecular, thiab particle loj faib. Feem ntau, HPMC nthuav tawm:
Zoo heev film-forming zog
Thermal gelation cwj pwm
Muaj peev xwm tuav tau dej
Stability tshaj pH dav
Compatibility nrog rau lwm yam polymers thiab additives
Non-ionic xwm, ua rau nws sib xws nrog ntau yam khoom xyaw
3. Synthesis ntawm HPMC:
Lub synthesis ntawm HPMC muaj ob peb kauj ruam:
Kev npaj Alkali cellulose: Cellulose yog kho nrog cov tshuaj alkaline los tsim alkali cellulose.
Etherification: Alkali cellulose reacts nrog propylene oxide thiab methyl chloride los qhia hydroxypropyl thiab methyl pawg mus rau cov pob txha cellulose.
Ntxuav thiab purification: Cov khoom uas tshwm sim yog ntxuav, neutralized, thiab purified kom tshem tawm impurities.
Kev ziab: Lub HPMC purified yog qhuav kom tau txais cov khoom kawg hauv daim ntawv hmoov.
4. Kev siv ntawm HPMC:
HPMC pom cov ntawv thov thoob plaws hauv ntau qhov kev lag luam:
Pharmaceuticals: HPMC feem ntau yog siv los ua cov khoom siv tshuaj hauv cov ntsiav tshuaj txheej, tshuaj tswj-tso formulations, ophthalmic npaj, thiab suspensions. Nws ua hauj lwm raws li ib tug binder, thickener, zaj duab xis qub, thiab sustained-tso tus neeg saib xyuas nyob rau hauv ntau npaum li cas cov ntaub ntawv.
Kev lag luam khoom noj khoom haus: Hauv kev lag luam khoom noj khoom haus, HPMC yog siv los ua cov thickener, stabilizer, emulsifier, thiab noo noo tuav tus neeg sawv cev hauv cov khoom xws li cov khoom ci, khoom noj siv mis, kua ntses, thiab khoom qab zib. Nws txhim kho kev ntxhib los mos, txee lub neej, thiab qhov ncauj qhov ntswg hauv cov khoom noj.
Kev tsim kho: HPMC yog cov khoom tseem ceeb hauv kev tsim kho cov ntaub ntawv xws li cement-based mortars, pobzeb adhesives, thiab gypsum-based khoom. Nws ua raws li tus neeg sawv cev tuav dej, txhim kho kev ua haujlwm, txo qis qis, thiab txhim kho adhesion hauv kev tsim kho.
Tshuaj pleev ib ce: HPMC yog siv rau hauv cov tshuaj pleev ib ce thiab cov khoom tu tus kheej ua cov thickener, stabilizer, thiab zaj duab xis-tsim tus neeg sawv cev hauv cov khoom xws li cream, tshuaj pleev ib ce, tshuaj zawv plaub hau, thiab gels. Nws imparts viscosity, txhim khu kev ntxhib los mos, thiab muab ib tug du, tsis-greasy xav.
Lwm Daim Ntawv Thov: HPMC tseem ua haujlwm hauv textile printing, ceramics, paints, detergents, thiab ua lub roj nplua nyeem nyob rau hauv ntau yam kev lag luam.
5. Kev Pom Zoo thiab Kev Sib Tw Yav Tom Ntej:
Qhov kev thov rau HPMC yuav tsum tau nce ntxiv vim nws cov khoom siv tau ntau yam thiab ntau yam kev siv. Txawm li cas los xij, cov kev sib tw xws li kev hloov pauv ntawm tus nqi raw khoom, kev tswj hwm kev txwv, thiab kev sib tw los ntawm lwm cov polymers tuaj yeem cuam tshuam kev lag luam. Kev tshawb nrhiav kev siv zog yog tsom rau kev txhim kho HPMC qhov kev ua tau zoo, tshawb nrhiav cov kev sib txuas kom ruaj khov, thiab nthuav dav nws cov ntawv thov hauv cov haujlwm tshiab xws li biomedicine thiab nanotechnology.
Hydroxypropyl Methylcellulose (HPMC) yog ib qho tseem ceeb polymer nrog ntau yam kev siv thoob plaws ntau qhov kev lag luam. Nws cov qauv tshwj xeeb, cov khoom siv, thiab kev sib txuas ua rau nws yog ib qho tseem ceeb ntawm cov khoom siv tshuaj, khoom noj khoom haus, khoom siv, tshuaj pleev ib ce, thiab ntau yam kev lag luam. Raws li kev tshawb fawb thiab kev tsim kho txuas ntxiv mus, HPMC tau npaj los ua tus tseem ceeb hauv kev lag luam polymer, muab cov kev daws teeb meem tshiab los ua kom tau raws li kev xav tau ntawm kev lag luam.
Post lub sij hawm: Mar-05-2024