HPMC yog dab tsi?

Hydroxypropyl methylcellulose (HPMC) yog ntau yam polymer muab tau los ntawm cellulose, ib txwm tshwm sim polysaccharide pom nyob rau hauv cell phab ntsa ntawm cov nroj tsuag. Nws yog feem ntau siv nyob rau hauv ntau yam lag luam xws li tshuaj, khoom noj khoom haus, tshuaj pleev ib ce, kev tsim kho, thiab ntau dua vim nws cov khoom tshwj xeeb.

HPMC yog tsim los ntawm kev hloov kho cellulose los ntawm cov tshuaj tiv thaiv etherification. Tshwj xeeb, nws yog tsim los ntawm kev kho cellulose nrog kev sib xyaw ntawm propylene oxide thiab methyl chloride los qhia hydroxypropyl thiab methyl pawg mus rau hauv cov pob txha cellulose. Cov txheej txheem no ua rau muaj dej-soluble polymer nrog cov khoom zoo dua qub piv rau cov cellulose ib txwm muaj.

Txheej txheem ntau lawm:

Kev tsim tawm ntawm HPMC suav nrog ob peb kauj ruam:

Cellulose Sourcing: Cellulose, feem ntau yog los ntawm cov ntaub ntoo los yog paj rwb, ua cov khoom pib.

Etherification: Cellulose tau dhau los ua etherification, qhov twg nws hnov ​​​​mob nrog propylene oxide thiab methyl chloride nyob rau hauv kev tswj xyuas kom paub txog hydroxypropyl thiab methyl pawg.

Purification: Cov khoom lag luam tau dhau los ua cov kauj ruam purification kom tshem tawm cov impurities thiab cov khoom tsis zoo.

Kev ziab thiab Milling: Lub HPMC purified yog ces qhuav thiab milled rau hauv hmoov zoo los yog granules, nyob ntawm seb qhov kev thov.

HPMC nthuav tawm ntau yam khoom, ua rau nws haum rau ntau yam kev siv:

Dej Solubility: HPMC yog soluble nyob rau hauv dej txias, tsim kom meej, viscous daws. Lub solubility tuaj yeem hloov kho los ntawm kev hloov kho qib ntawm kev hloov pauv (DS) ntawm hydroxypropyl thiab methyl pawg.

Zaj duab xis-Forming: Nws tuaj yeem tsim cov yeeb yaj kiab hloov tau yooj yim thiab cohesive thaum ziab, ua rau nws tsim nyog rau txheej txheej hauv kev lag luam tshuaj thiab zaub mov.

Thickening: HPMC yog ib tus neeg ua haujlwm thickening zoo, muab viscosity tswj nyob rau hauv ntau yam formulations xws li tshuaj pleev, cream, thiab xim.

Stability: Nws nthuav tawm cov tshuaj lom neeg ruaj khov thiab ua haujlwm rau microbial degradation.

Compatibility: HPMC yog sib xws nrog ntau yam ntawm lwm cov khoom xyaw, xws li surfactants, ntsev, thiab preservatives.

HPMC pom ntau daim ntawv thov thoob plaws kev lag luam sib txawv:

Pharmaceuticals: Nws yog feem ntau siv los ua cov ntawv khi, cov yeeb yaj kiab-txheej txheej, viscosity modifier, thiab sustained-release matrix hauv cov ntsiav tshuaj formulations.

Kev lag luam khoom noj khoom haus: HPMC ua hauj lwm ua ib lub thickener, stabilizer, thiab emulsifier hauv cov khoom noj xws li kua ntses, hnav khaub ncaws, thiab khoom qab zib.

Kev tsim kho: Hauv kev tsim kho kev lag luam, HPMC yog siv los ua cov thickener hauv cov khoom siv cement, txhim kho kev ua haujlwm thiab kev ua kom zoo.

Cov Khoom Siv Kho Tus Kheej: Nws muaj nyob rau hauv cov tshuaj pleev ib ce, tshuaj zawv plaub hau, thiab tshuaj txhuam hniav ua tus neeg sawv cev thickening, emulsifier, thiab zaj duab xis qub.

Xim thiab Txheej: HPMC txhim kho cov khoom rheological ntawm cov xim thiab txheej, txhim kho lawv daim ntawv thov thiab kev ua haujlwm.

HPMC, muab los ntawm cellulose los ntawm etherification cov tshuaj tiv thaiv, yog ntau yam polymer nrog ntau yam kev siv thoob plaws ntau yam lag luam. Nws cov khoom tshwj xeeb, xws li dej solubility, muaj peev xwm ua yeeb yaj kiab, thiab cov khoom ua kom tuab, ua rau nws tseem ceeb hauv cov tshuaj, khoom noj, kev tsim kho, thiab cov khoom siv tu tus kheej.