Hydroxypropylmethylcellulose (HPMC) yog ntau yam thiab ntau yam sib xyaw ua ke uas belongs rau tsev neeg cellulose ether. Nws yog muab los ntawm cellulose, ib tug natural polymer pom nyob rau hauv cov nroj tsuag cell phab ntsa. HPMC yog dav siv nyob rau hauv ntau yam lag luam xws li tshuaj, khoom noj khoom haus, kev tsim kho thiab tshuaj pleev ib ce vim nws cov khoom tshwj xeeb thiab ntau yam zoo.
1. Pharmaceutical kev lag luam:
A. Sustained release npaj:
HPMC tau siv dav hauv kev lag luam tshuaj vim nws muaj peev xwm tsim cov gel matrix thaum hydrated. Cov cuab yeej no muaj txiaj ntsig tshwj xeeb hauv kev txhim kho cov tshuaj tiv thaiv-tso tawm cov tshuaj. Los ntawm kev tswj cov viscosity thiab gelation tus nqi ntawm HPMC, cov chaw tsim tshuaj muaj peev xwm ua tiav cov tshuaj tso tawm txuas ntxiv, txhim kho kev ua raws li tus neeg mob thiab txo cov koob tshuaj ntau zaus.
b. Nyias zaj duab xis txheej:
HPMC feem ntau yog siv los ua cov yeeb yaj kiab txheej rau cov ntsiav tshuaj. Nws muab cov txheej txheem du, zoo ib yam uas txhim kho cov tsos ntawm cov ntsiav tshuaj, npog qhov saj ntawm cov tshuaj, thiab tiv thaiv nws los ntawm ib puag ncig yam. Cov yeeb yaj kiab tsim cov khoom ntawm HPMC pab txhim kho tshuaj stability thiab bioavailability.
C. Tswj Kev Xa Tshuaj:
Lub biocompatibility thiab inert xwm ntawm HPMC ua rau nws haum rau siv nyob rau hauv kev tswj cov tshuaj xa systems. Nws tuaj yeem siv ua ke nrog lwm cov polymers los hloov kho cov tshuaj tso tawm kinetics, tso cai rau kev tswj hwm tus nqi xa tshuaj thiab txo qhov kev pheej hmoo ntawm kev mob tshwm sim.
d. Tablet binder:
HPMC ua raws li cov ntsiav tshuaj binder zoo, pab muab cov nplaum nplaum rau cov ntsiav tshuaj formulations. Nws ua kom zoo compaction ntawm cov khoom xyaw, uas ua rau uniform hardness thiab kev ncaj ncees ntawm cov ntsiav tshuaj.
2. Khoom noj khoom haus kev lag luam:
A. Thickeners thiab gelling agents:
Hauv kev lag luam khoom noj khoom haus, HPMC yog siv los ua thickener thiab gelling tus neeg sawv cev. Nws muab cov khoom noj uas xav tau kev ntxhib los mos thiab txhim kho nws qhov zoo tag nrho. HPMC feem ntau siv rau hauv cov khoom xws li kua ntses, kua zaub thiab khoom qab zib kom ua tiav qhov xav tau sib xws.
b. Kev hloov rog:
HPMC tuaj yeem siv los hloov cov rog hauv qee yam khoom noj, pab txhim kho cov rog tsawg lossis tsis muaj rog. Qhov no yog qhov tseem ceeb tshwj xeeb hauv cov ntsiab lus ntawm kev daws teeb meem kev noj qab haus huv cuam tshuam nrog kev noj roj ntau dhau.
C. emulsification:
Vim nws cov khoom emulsifying, HPMC yog siv los tsim cov khoom noj emulsified. Nws pab stabilize emulsions, tiv thaiv theem sib cais thiab xyuas kom meej ib homogeneous khoom.
d. Polishing tus neeg sawv cev:
HPMC yog siv los ua glazing neeg sawv cev hauv kev lag luam khoom noj khoom haus los muab cov ci ntsa iab thiab pom kev zoo rau cov khoom qab zib, txiv hmab txiv ntoo thiab lwm yam khoom noj.
3. Kev tsim kho kev lag luam:
A. Pobzeb nplaum:
HPMC yog cov khoom tseem ceeb hauv cov nplais nplaum thiab ua raws li cov kua nplaum thiab cov dej khaws cia. Nws txhim kho kev ua haujlwm ntawm cov khoom sib txuas, ua kom kev tsim kho yooj yim dua thiab txhim kho daim ntawv cog lus.
b. Cement mortar:
Hauv cov cement-based mortars, HPMC yog siv los txhim kho cov dej tuav, ua haujlwm tau zoo thiab adhesion. Nws pab txhim kho tag nrho cov khoom ntawm mortar, ua kom yooj yim rau kev tuav thiab ua kom zoo dua adhesion rau saum npoo.
C. Self-leveling compounds:
HPMC tau muab tso rau hauv qhov sib xyaw ua ke ntawm tus kheej los tswj cov viscosity thiab txhim kho cov yam ntxwv ntws. Qhov no yog qhov tseem ceeb kom ua tiav qhov du, theem saum npoo thaum thov ntawm cov plag tsev.
d. Gypsum thiab stucco:
Ntxiv HPMC rau gypsum thiab stucco formulations txhim kho adhesion, workability thiab dej tuav. Nws pab txhim kho lub zuag qhia tag nrho qhov zoo ntawm qhov tiav tiav, txo qhov kev pheej hmoo ntawm cov kab nrib pleb thiab ua kom durability.
4. Kev lag luam tshuaj pleev ib ce:
A. Thickeners nyob rau hauv cream thiab lotions:
HPMC feem ntau yog siv los ua tus neeg sawv cev thickening hauv cov tshuaj pleev ib ce xws li cream thiab tshuaj pleev ib ce. Nws muab cov khoom ib tug du, creamy kev ntxhib los mos thiab txhim khu nws cov khoom sensory.
b. Film-forming agents hauv cov khoom tu plaub hau:
Hauv cov khoom tu plaub hau xws li cov plaub hau gels thiab styling cream, HPMC ua tus neeg sawv cev ua yeeb yaj kiab. Nws pab tsim cov yeeb yaj kiab hloov tau yooj yim ntawm cov plaub hau, pab txhim kho tuav thiab tswj tau.
C. Emulsion stabilizer:
Cov khoom ruaj khov ntawm HPMC ua rau nws muaj txiaj ntsig zoo hauv emulsion formulations los tiv thaiv theem sib cais thiab ua kom cov khoom ruaj khov nyob rau lub sijhawm.
d. Tswj kev tso tawm hauv cov tshuaj pleev ib ce:
Zoo ib yam li nws siv hauv cov tshuaj, HPMC tuaj yeem siv rau hauv cov tshuaj pleev ib ce kom ua tiav cov tshuaj tiv thaiv tawm ntawm cov khoom xyaw nquag. Qhov no yog qhov tseem ceeb tshwj xeeb tshaj yog rau cov khoom tu tawv nqaij uas xav tau kev tso tawm ntawm cov khoom sib txuas.
5. Cov txiaj ntsig ntxiv:
A. Kev tuav dej:
HPMC muaj cov khoom tuav dej zoo heev, ua rau nws muaj txiaj ntsig hauv ntau yam kev siv uas tswj cov dej noo yog qhov tseem ceeb. Qhov no yog tshwj xeeb tshaj yog zoo nyob rau hauv tej formulations nyob rau hauv kev tsim kho kev lag luam thiab nyob rau hauv cov zaub mov thiab tshuaj pleev ib ce industries.
b. Biodegradability:
HPMC yog ib qho biodegradable polymer uas yog nyob rau hauv txoj kab nrog kev loj hlob tseem ceeb ntawm cov ntaub ntawv ib puag ncig thiab ruaj khov. Nws cov khoom biodegradable txo qhov cuam tshuam ib puag ncig, ua rau nws xaiv thawj zaug rau qee yam kev siv.
C. Compatibility nrog lwm cov polymers:
HPMC muaj kev sib raug zoo nrog ntau yam ntawm lwm cov polymers, tso cai rau cov txheej txheem nyuaj tsim raws li kev thov tshwj xeeb.
d. Non-toxic thiab inert:
HPMC suav hais tias tsis muaj tshuaj lom thiab tsis muaj zog, ua rau nws muaj kev nyab xeeb rau kev siv tshuaj, khoom noj, tshuaj pleev ib ce thiab lwm yam kev siv uas kev nyab xeeb ntawm cov neeg siv khoom tseem ceeb.
Hydroxypropyl methylcellulose (HPMC) sawv tawm hauv ntau qhov kev lag luam ua ntau yam thiab muaj txiaj ntsig zoo. Nws pab tsim cov txheej txheem tswj-tso tawm, txhim kho kev ua tau zoo ntawm cov khoom noj thiab tshuaj pleev ib ce, thiab txhim kho cov khoom ntawm cov khoom siv tsim kho, qhia txog nws cov kev siv ntau yam thiab qhov tseem ceeb hauv cov txheej txheem tsim khoom niaj hnub no. Raws li kev lag luam txuas ntxiv mus, HPMC yuav tseem yog cov khoom tseem ceeb hauv kev tsim cov khoom tshiab thiab cov khoom zoo.
Post lub sij hawm: Dec-18-2023