Hydroxypropyl methylcellulose (HPMC) tsis yog plasticizer nyob rau hauv cov kev xav ib txwm muaj. Nws yog ib qho cellulose derivative feem ntau siv hauv kev lag luam tshuaj, zaub mov, kev tsim kho thiab kev kho tus kheej. Thaum nws tsis ua zoo li cov plasticizers siv hauv polymers, nws muaj qee yam khoom uas tuaj yeem sib tw cov teebmeem ntawm plasticizing hauv qee daim ntawv thov.
Txhawm rau tshawb xyuas tag nrho cov ncauj lus ntawm HPMC thiab nws lub luag haujlwm hauv ntau qhov kev lag luam, peb tuaj yeem nkag siab txog nws cov qauv tshuaj, khoom siv, kev siv, thiab qhov zoo thiab qhov tsis zoo. Kev nkag siab zoo ntawm HPMC yuav muab kev nkag siab rau nws cov ntawv thov sib txawv thiab vim li cas nws thiaj suav tias yog cov khoom muaj txiaj ntsig hauv ntau cov qauv.
Cov qauv tshuaj thiab cov khoom ntawm HPMC
Chemical structure:
HPMC yog ib tug semi-synthetic polymer muab los ntawm cellulose, ib tug natural polymer pom nyob rau hauv cov nroj tsuag cell phab ntsa. Hydroxypropyl thiab methyl pawg tau qhia los ntawm kev hloov kho tshuaj. Qhov kev hloov pauv no hloov pauv lub cev thiab tshuaj lom neeg ntawm cellulose, ua rau cov khoom sib txuas nrog kev ua haujlwm zoo dua qub.
yam ntxwv:
Hydrophilic: HPMC yog dej-soluble thiab hygroscopic heev, ua rau nws haum rau ntau yam formulations uas yuav tsum tau dej tuav los yog tswj kev tso tawm.
Zaj duab xis-forming: Nws muaj zaj duab xis-tsim cov khoom uas tsim cov yeeb yaj kiab tiv thaiv thaum siv rau saum npoo, ua rau nws muaj txiaj ntsig zoo hauv cov tshuaj coatings thiab cov ntaub ntawv tsim kho.
Tus neeg sawv cev Thickening: HPMC feem ntau yog siv los ua tus neeg sawv cev thickening hauv cov tshuaj aqueous. Nws viscosity nce nrog concentration, tso cai rau kev tswj kom zoo sib xws ntawm cov kua formulations.
Kub rhiab heev: Qee qib ntawm HPMC yog thermally thim rov qab, txhais tau tias lawv tuaj yeem hloov pauv theem hloov nrog kev hloov pauv hauv qhov kub thiab txias.
Kev siv HPMC hauv kev lag luam sib txawv
1. Pharmaceutical kev lag luam:
Tablet Txheej: HPMC feem ntau yog siv los ua cov khoom siv txheej rau cov ntsiav tshuaj hauv kev lag luam tshuaj. Nws muab cov txheej txheem tiv thaiv, tswj cov tshuaj tso tawm, thiab txhim kho cov ntsiav tshuaj zoo li.
Ophthalmic Solutions: Hauv qhov muag tee thiab cov tshuaj kho qhov muag, HPMC tuaj yeem txhim kho viscosity thiab txhim kho lub sijhawm tuav ntawm lub qhov muag.
2. Khoom noj khoom haus kev lag luam:
Tus neeg sawv cev Thickening: HPMC yog siv los ua cov khoom ua kom tuab hauv ntau yam khoom noj, nrog rau cov kua ntses, kua zaub thiab cov khoom noj siv mis.
Emulsifier: Hauv qee daim ntawv thov zaub mov, HPMC tuaj yeem ua raws li emulsifier, txhim kho kev ruaj ntseg ntawm emulsion.
3. Kev tsim kho kev lag luam:
Pobzeb Adhesives: Qhov sib ntxiv ntawm HPMC rau pobzeb nplaum txhim kho kev ua haujlwm, dej tuav thiab daim ntawv cog lus.
Mortars thiab Plasters: Siv rau hauv cov khoom siv xws li mortars thiab plasters los txhim kho adhesion thiab workability.
4. Cov khoom siv tu tus kheej:
Cov tshuaj pleev ib ce: Hauv cov tshuaj pleev, tshuaj pleev thiab lwm cov tshuaj pleev ib ce, HPMC pab txhim kho kev ntxhib los mos, ruaj khov thiab tawv nqaij ntawm cov khoom.
Cov Khoom Siv Kho Hniav: HPMC muaj nyob hauv qee cov khoom tu plaub hau vim nws cov yeeb yaj kiab tsim thiab ua kom txias.
Qhov zoo thiab qhov tsis zoo ntawm HPMC
qhov zoo:
Biocompatibility: HPMC feem ntau suav hais tias muaj kev nyab xeeb rau tib neeg noj thiab siv dav hauv kev siv tshuaj thiab zaub mov.
Versatility: Nws muaj ntau yam khoom thiab tsim nyog rau ntau yam kev lag luam thiab kev tsim qauv.
Kev tuav dej: Qhov dej hydrophilic ntawm HPMC pab hauv kev tuav dej, uas tuaj yeem muaj txiaj ntsig zoo hauv qee yam kev siv.
tsis txaus:
Tus nqi: HPMC tuaj yeem raug nqi kim dua piv rau lwm cov tshuaj ntxiv.
Temperature Sensitivity: Vim muaj qhov hloov pauv tau ntawm qee qib HPMC, qee cov qauv yuav raug cuam tshuam los ntawm kev hloov pauv kub.
nyob rau hauv xaus
Txawm hais tias HPMC tsis yog plasticizer hauv kev xav ib txwm muaj, nws cov khoom tshwj xeeb ua rau nws muaj txiaj ntsig zoo hauv ntau qhov kev lag luam. Nws qhia tau hais tias nws muaj peev xwm ua tau raws li cov yeeb yaj kiab yav dhau los, thickener thiab dej tuav tus neeg sawv cev hauv kev siv tshuaj, khoom noj khoom haus, kev tsim kho thiab kev saib xyuas tus kheej. Nkag siab txog cov qauv tshuaj, cov khoom siv, thiab kev siv ntawm HPMC yog qhov tseem ceeb rau cov kws tsim qauv thiab cov kws tshawb fawb nrhiav kev txhim kho cov qauv kom tau raws li cov kev xav tau tshwj xeeb. Qhov zoo ntawm biocompatibility thiab versatility ntau dua qhov muaj peev xwm tsis zoo, ua rau HPMC yog qhov kev xaiv nrov hauv ntau qhov kev lag luam.
Post lub sij hawm: Dec-14-2023