HPMC siv hauv Pharmaceuticals
Hydroxypropyl Methyl Cellulose (HPMC) yog siv dav hauv kev lag luam kws tshuaj rau ntau yam kev siv, vim nws cov khoom siv ntau yam. Nov yog qee qhov kev siv tseem ceeb ntawm HPMC hauv kev siv tshuaj:
1. Ntsiav tshuaj ntsiav tshuaj
1.1 Lub luag haujlwm hauv zaj duab xis txheej
- Kev Ua Zaj Duab Xis: HPMC feem ntau yog siv los ua tus neeg ua yeeb yaj kiab hauv cov ntsiav tshuaj txheej. Nws muab cov txheej nyias nyias, zoo ib yam, thiab tiv thaiv txheej ntawm cov ntsiav tshuaj saum npoo, txhim kho cov tsos, ruaj khov, thiab yooj yim nqos.
1.2 Enteric Txheej
- Kev Tiv Thaiv Enteric: Hauv qee cov qauv, HPMC yog siv rau hauv cov txheej txheem enteric, uas tiv thaiv cov ntsiav tshuaj los ntawm plab acid, tso cai rau cov tshuaj tso tawm hauv cov hnyuv.
2. Tswj-tso cov qauv
2.1 Sustained Tso
- Tswj Kev Tso Tawm Tshuaj: HPMC yog ua haujlwm nyob rau hauv cov ntawv tso tawm kom ruaj khov los tswj qhov tso tawm ntawm cov tshuaj nyob rau lub sijhawm ntev, ua rau muaj kev kho mob ntev.
3. Cov kua dej ntawm qhov ncauj thiab cov tshuaj ncua
3.1 Thickening Agent
- Thickening: HPMC yog siv los ua tus neeg sawv cev thickening hauv cov kua hauv qhov ncauj thiab tshem tawm, txhim kho lawv cov viscosity thiab txhim kho palatability.
4. Cov tshuaj kho qhov muag pom kev
4.1 Lubricating Agent
- Lubrication: Hauv kev daws teeb meem ophthalmic, HPMC ua haujlwm ua tus neeg sawv cev lubricating, txhim kho cov nyhuv moistening ntawm lub qhov muag thiab txhawb kev nplij siab.
5. Kev npaj tshuaj
5.1 Gel Tsim
- Gel Formulation: HPMC yog ua hauj lwm nyob rau hauv lub formulation ntawm tshuaj pleev gels, muab cov yam xav tau rheological zog thiab pab nyob rau hauv lub txawm faib ntawm cov active ingredient.
6. Oral Disintegrating Tablets (ODT)
6.1 Kev Txhim Kho Kev Txhim Kho
- Disintegration: HPMC yog siv rau hauv kev tsim cov ntsiav tshuaj ntawm qhov ncauj los txhim kho lawv cov khoom tawg, ua rau kom tawg sai hauv lub qhov ncauj.
7. Cov Tshuaj Kho Qhov Muag thiab Cov Kua Muag Hloov
7.1 viscosity tswj
- Viscosity Enhancement: HPMC yog siv los tswj cov viscosity ntawm qhov muag tee thiab cov kua muag hloov, kom ntseeg tau tias daim ntawv thov thiab khaws cia ntawm qhov muag.
8. Kev txiav txim siab thiab ceev faj
8.1 Dosage
- Dosage Control: Qhov ntau npaum li cas ntawm HPMC hauv cov tshuaj formulations yuav tsum tau ua tib zoo tswj kom ua tiav cov khoom uas xav tau yam tsis muaj kev cuam tshuam rau lwm tus yam ntxwv.
8.2 Compatibility
- Compatibility: HPMC yuav tsum sib haum nrog lwm cov khoom xyaw tshuaj, excipients, thiab active compounds kom ruaj khov thiab ua tau zoo.
8.3 Txoj Cai Ua Raws Cai
- Kev txiav txim siab txog kev tswj hwm: Cov tshuaj tsim tshuaj uas muaj HPMC yuav tsum ua raws li cov qauv kev cai thiab cov lus qhia kom muaj kev nyab xeeb thiab ua tau zoo.
9. Cov lus xaus
Hydroxypropyl Methyl Cellulose yog cov khoom siv ntau yam thiab siv dav hauv kev lag luam kws tshuaj, pab txhawb cov ntsiav tshuaj txheej, tswj-tso formulations, kua qhov ncauj, tshuaj kho qhov muag, tshuaj pleev, thiab lwm yam. Nws film-forming, thickening, thiab tswj-tso cov khoom ua rau nws muaj txiaj ntsig hauv ntau yam kev siv tshuaj. Ua tib zoo txiav txim siab txog ntau npaum li cas, kev sib raug zoo, thiab cov kev cai tswj hwm yog qhov tseem ceeb rau kev tsim cov khoom lag luam zoo thiab ua raws li cov tshuaj.
Post lub sij hawm: Jan-01-2024