Hydroxypropyl methylcellulose (HPMC) yog cov khoom siv ntau yam polymer nrog kev siv dav hauv ntau yam lag luam xws li tshuaj, kev tsim kho, khoom noj khoom haus, tshuaj pleev ib ce, thiab lwm yam. Nws muaj ntau yam khoom thiab kev ua haujlwm ua rau nws muaj txiaj ntsig zoo hauv ntau yam khoom. Nov yog qhov kev tshawb nrhiav qhov tob ntawm HPMC:
1. Yam ntxwv ntawm HPMC:
Chemical Structure: HPMC yog muab los ntawm cellulose, ib tug natural polymer pom nyob rau hauv cov nroj tsuag. Nws yog tsim los ntawm kev hloov kho cellulose nrog propylene oxide thiab methyl chloride. Qib ntawm kev hloov ntawm hydroxypropyl thiab methoxy pawg txiav txim siab nws cov khoom.
Solubility: HPMC yog soluble nyob rau hauv dej nyob rau hauv ntau qhov kub thiab txias. Solubility nyob ntawm qhov kev hloov pauv thiab qhov hnyav molecular ntawm cov polymer. Kev hloov pauv ntau dua ua rau muaj dej ntau ntxiv.
Viscosity: HPMC nthuav tawm pseudoplastic lossis shear-thinning tus cwj pwm, txhais tau tias nws cov viscosity txo qis hauv kev ntxhov siab. Lub viscosity ntawm HPMC cov kev daws teeb meem tuaj yeem hloov kho los ntawm kev hloov pauv tsis xws li qhov hnyav molecular, qib ntawm kev hloov pauv, thiab concentration.
Zaj duab xis tsim: HPMC cov ntaub ntawv ntshiab thiab hloov tau yooj yim thaum nrum los ntawm kev daws teeb meem. Cov khoom ua yeeb yaj kiab tuaj yeem hloov kho los ntawm kev kho cov polymer concentration thiab muaj cov plasticizers.
Thermal stability: HPMC muaj thermal stability zoo, nrog rau decomposition kub feem ntau tshaj 200 ° C. Qhov no ua rau nws haum rau ntau txoj kev ua, suav nrog kub yaj extrusion thiab txhaj tshuaj molding.
Hydrophilicity: Vim nws qhov xwm txheej hydrophilic, HPMC tuaj yeem nqus tau thiab khaws cov dej ntau. Cov cuab yeej no muaj txiaj ntsig zoo hauv cov ntawv thov xws li kev tswj hwm-tso tshuaj xa khoom thiab ua tus neeg sawv cev thickening hauv cov tshuab aqueous.
Compatibility: HPMC yog sib xws nrog ntau yam ntawm lwm yam ntaub ntawv, nrog rau lwm yam polymers, plasticizers, thiab active tshuaj cov khoom xyaw (APIs). Qhov kev sib raug zoo no tso cai rau cov txheej txheem nyuaj los tsim nrog cov yam ntxwv tshwj xeeb.
Non-ionic Properties: HPMC yog non-ionic polymer, uas txhais tau tias nws tsis nqa hluav taws xob. Cov cuab yeej no txo qis kev sib cuam tshuam nrog cov tsiaj raug nqi hauv kev tsim thiab txhim kho nws txoj kev ruaj ntseg hauv kev daws teeb meem.
2.HPMC muaj nuj nqi:
Binders: Nyob rau hauv cov ntsiav tshuaj formulations, HPMC ua raws li ib tug binder, txhawb adhesion ntawm hais thiab ua rau cov neeg kho tshuab lub zog ntawm cov ntsiav tshuaj. Nws kuj pab cov ntsiav tshuaj disintegrate tom qab noj.
Zaj duab xis txheej: HPMC yog dav siv los ua cov yeeb yaj kiab txheej rau cov ntsiav tshuaj thiab tshuaj ntsiav. Nws tsim cov txheej txheem sib xws, tiv thaiv lub ntsej muag uas npog qhov saj thiab tsw ntawm cov tshuaj, txhim khu kev ruaj ntseg, thiab yooj yim rau nqos.
Kev tso tawm tsis tu ncua: HPMC tuaj yeem siv los tswj tus nqi tso tawm ntawm cov tshuaj los ntawm cov ntawv siv tshuaj. Los ntawm hydrating los tsim ib txheej gel, HPMC tuaj yeem ncua sijhawm tso tshuaj thiab muab cov txiaj ntsig kho tau zoo.
Viscosity Modifier: Hauv cov tshuab aqueous, HPMC ua raws li kev hloov kho viscosity lossis thickener. Nws imparts pseudoplastic flow cwj pwm, txhim kho kev ruaj ntseg thiab kev ua haujlwm ntawm cov formulations xws li cream, lotions thiab gels.
Suspending tus neeg sawv cev: HPMC yog siv los txhim kho kev ncua ntawm cov khoom tsis sib xws hauv cov qauv ua kua. Nws tiv thaiv kev daws teeb meem los ntawm kev ua kom cov viscosity ntawm cov theem tas mus li thiab txhim kho particle dispersion.
emulsifier: Hauv emulsion formulations, HPMC stabilizes lub interface ntawm cov roj thiab dej theem, tiv thaiv theem sib cais thiab emulsification. Nws txhim kho kev ruaj ntseg thiab txee lub neej ntawm cov tshuaj pleev ib ce hauv cov khoom xws li cream, tshuaj pleev thiab tshuaj pleev.
Hydrogel Tsim: HPMC tuaj yeem tsim cov hydrogels thaum hydrated, ua rau nws muaj txiaj ntsig zoo hauv kev hnav khaub ncaws, tiv thaiv lo ntsiab muag, thiab kev xa tshuaj. Cov hydrogels no muab qhov chaw ntub dej rau kev kho qhov txhab thiab tuaj yeem thauj cov tshuaj rau kev xa hauv zos.
Thickening Agent: HPMC feem ntau yog siv los ua cov khoom ua kom tuab hauv cov khoom noj xws li kua ntses, hnav khaub ncaws thiab khoom qab zib. Nws imparts ib tug du kev ntxhib los mos thiab txhim khu saj yam tsis hloov tsw los yog khoom noj khoom haus cov ntsiab lus.
Cov Khoom Siv Ntxiv: Hauv kev tsim kho kev lag luam, HPMC yog siv los ua cov dej tuav hauv cov cement-based mortars thiab plasters. Nws txhim kho kev ua haujlwm, adhesion, thiab txo qhov tawg los ntawm kev ua kom dej evaporation qeeb.
Surface Modifier: HPMC tuaj yeem hloov kho cov khoom saum npoo ntawm cov khoom substrates xws li ntawv, textiles thiab ceramics. Nws txhim kho cov luam ntawv, adhesion thiab barrier zog ntawm coatings thiab films.
Hydroxypropylmethylcellulose (HPMC) yog ntau yam polymer nrog ntau yam khoom thiab ua haujlwm. Nws solubility, viscosity, film-forming peev xwm thiab compatibility ua rau nws ib tug indispensable muaj nyob rau hauv ntau daim ntawv thov nyob rau hauv industries. Los ntawm kev siv tshuaj mus rau kev tsim kho, khoom noj rau cov tshuaj pleev ib ce, HPMC tseem ua lub luag haujlwm tseem ceeb hauv kev txhim kho cov khoom lag luam thiab kev ua tau zoo. Raws li kev tshawb fawb thiab thev naus laus zis ua ntej, ntau yam thiab kev siv hluav taws xob ntawm HPMC tuaj yeem nthuav dav ntxiv, tsav kev tsim kho tshiab hauv kev tsim qauv thiab kev tsim khoom.
Post lub sij hawm: Feb-23-2024