Hydroxypropyl methylcellulose (HPMC) thiab hypromellose yog qhov tseeb tib yam, thiab cov ntsiab lus feem ntau siv sib hloov. Cov no yog cov npe nyuaj rau ntau hom cellulose-raws li polymers uas muaj ntau yam kev siv hauv ntau yam lag luam xws li tshuaj, zaub mov thiab tshuaj pleev ib ce.
1.Chemical qauv thiab muaj pes tsawg leeg:
Hydroxypropylmethylcellulose (HPMC) yog ib qho kev hloov kho hluavtaws ntawm cellulose, ib qho polymer ntuj pom nyob rau hauv cov phab ntsa ntawm cov nroj tsuag. Cov qauv tshuaj ntawm HPMC tau txais los ntawm kev qhia hydroxypropyl thiab methyl pawg raws li cellulose. Cov pab pawg hydroxypropyl ua rau cellulose ntau soluble hauv dej, thiab pawg methyl txhim kho nws txoj kev ruaj ntseg thiab txo nws cov reactivity.
2. Cov txheej txheem tsim khoom:
Kev tsim cov hydroxypropyl methylcellulose suav nrog kev kho cov cellulose nrog propylene oxide los qhia cov pab pawg hydroxypropyl thiab tom qab ntawd nrog methyl chloride ntxiv methyl pawg. Qhov degree ntawm kev hloov pauv (DS) ntawm hydroxypropyl thiab methyl tuaj yeem hloov kho thaum lub sijhawm tsim khoom, ua rau cov qib sib txawv ntawm HPMC nrog cov khoom sib txawv.
3. Lub cev muaj zog:
HPMC yog cov hmoov dawb rau me ntsis tawm-dawb, tsis muaj ntxhiab thiab tsis qab. Nws lub cev muaj zog, xws li viscosity thiab solubility, nyob ntawm seb qhov kev hloov pauv thiab qhov hnyav molecular ntawm cov polymer. Raws li ib txwm muaj, nws yooj yim soluble hauv dej, tsim cov pob tshab thiab tsis muaj xim.
4. Lub hom phiaj kho mob:
Ib qho ntawm cov kev siv tseem ceeb ntawm HPMC yog nyob rau hauv kev lag luam kws tshuaj. Nws yog dav siv raws li ib tug kws tshuaj excipient thiab plays ntau lub luag hauj lwm nyob rau hauv kev npaj tshuaj. HPMC feem ntau pom muaj nyob rau hauv cov ntaub ntawv ntawm qhov ncauj khoom noj xws li ntsiav tshuaj, tshuaj ntsiav, thiab tshuaj. Nws ua raws li ib tug binder, disintegrant, thiab tswj kev tso tawm tus neeg sawv cev, pab txhawb rau tag nrho cov stability thiab bioavailability ntawm cov tshuaj.
5. Lub luag haujlwm hauv kev tswj cov kev npaj tso tawm:
Lub peev xwm ntawm HPMC los tsim cov gels hauv cov tshuaj aqueous ua rau nws muaj txiaj ntsig hauv kev tswj-tso tshuaj formulations. Los ntawm kev sib txawv ntawm cov viscosity thiab gel-forming zog, cov kws tshawb fawb kws kho mob tuaj yeem tswj tau qhov tso tawm ntawm cov khoom xyaw nquag, yog li ua tiav cov tshuaj ua haujlwm ntev thiab ntev.
6. Daim ntawv thov hauv kev lag luam zaub mov:
Hauv kev lag luam zaub mov, HPMC yog siv los ua cov thickener, stabilizer thiab emulsifier. Nws txhim kho kev ntxhib los mos ntawm ntau yam khoom noj, nrog rau cov kua ntses, kua zaub thiab cov khoom noj siv mis. Tsis tas li ntawd, HPMC yog siv rau hauv gluten-dawb ci los txhim kho cov qauv thiab moisturizing zog ntawm gluten-dawb cov khoom.
7. Kev tsim kho thiab cov khoom siv hauv tsev:
HPMC yog siv nyob rau hauv kev tsim kho kev lag luam hauv cov khoom xws li pobzeb adhesives, cement-based plasters thiab gypsum-based cov ntaub ntawv. Nws txhim kho cov txheej txheem, kev tuav dej thiab cov khoom nplaum ntawm cov khoom no.
8. Tshuaj pleev ib ce thiab khoom tu tus kheej:
Hypromellose kuj yog ib qho khoom muaj nyob rau hauv cov tshuaj pleev ib ce thiab cov khoom tu tus kheej. Nws yog siv nyob rau hauv cream, tshuaj pleev ib ce thiab tshuaj zawv plaub hau vim nws thickening thiab stabilizing zog. Tsis tas li ntawd, nws pab txhim kho tag nrho kev ntxhib los mos thiab kev xav ntawm cov khoom.
9. Zaj duab xis txheej hauv tshuaj:
HPMC yog dav siv nyob rau hauv kev lag luam kws tshuaj rau zaj duab xis txheej ntawm cov ntsiav tshuaj. Cov ntsiav tshuaj zaj duab xis-coated muab cov tsos zoo, saj npog ntsej muag thiab tiv thaiv ib puag ncig yam. HPMC films muab cov txheej txheem du thiab zoo ib yam, txhim kho tag nrho cov khoom siv tshuaj zoo.
13. Xaus:
Hydroxypropyl methylcellulose (HPMC) thiab hypromellose xa mus rau tib lub cellulose-based polymer uas muaj ntau yam kev siv hauv tshuaj, khoom noj, tshuaj pleev ib ce, thiab kev tsim kho. Nws cov khoom tshwj xeeb, xws li solubility, stability thiab biodegradability, ua rau nws siv dav. Lub versatility ntawm HPMC nyob rau hauv txawv industries qhia nws qhov tseem ceeb raws li ib tug multifunctional khoom, thiab txuas ntxiv mus.kev tshawb nrhiav thiab kev tsim kho yuav nthuav tawm cov ntawv thov ntxiv yav tom ntej.
Cov lus qhia dav dav no yog tsim los muab cov ncauj lus kom ntxaws txog hydroxypropyl methylcellulose thiab hypromellose, qhia lawv qhov tseem ceeb hauv ntau qhov chaw, thiab qhia lawv lub luag haujlwm hauv kev tsim ntau yam khoom thiab cov qauv.
Post lub sij hawm: Dec-21-2023